于西安交通大学博士毕业后留校工作,2016.07至今工作于青岛大学附属医院,曾公派访学于美国宾夕法尼大学大学,长期从事口腔颌面外科的临床、教学及科研工作。目前荣获山东省口腔颌面外科领域首位泰山学者青年专家、齐鲁卫生与健康杰青、青岛大学卓越人才及青大附院高层次人才等称号;获中国抗癌协会科技二等奖、山东省科技进步二等奖及青岛市科技进步一等奖等;发表SCI学术论文50余篇,其中(含共同)第一作者和通讯作者文章35篇;主持国家自然科学基金、山东省重点研发项目等科研项目8项。
K. Sun, Y. Zhi, W. Ren, S. Li, J. Zheng, L. Gao, K. Zhi, Crosstalk between O-GlcNAcylation and ubiquitination: a novel strategy for overcoming cancer therapeutic resistance, Experimental hematology & oncology 13(1) (2024) 107.(IF:13.5,共同通讯作者)
Z. Zhu, W. Ren, S. Li, L. Gao, K. Zhi, Functional significance of O-linked N-acetylglucosamine protein modification in regulating autophagy, Pharmacological research 202 (2024) 107120.(IF:10.5,共同通讯作者)
K. Sun, K. Zhi, L. Gao, Refining neck dissection strategies in oral squamous cell carcinoma: a surgical perspective, International journal of surgery (London, England) 111(10) (2025) 7427-7428.(IF:10.1,通讯作者)
L. Gao, Q. Zhang, S. Li, J. Zheng, W. Ren, K. Zhi, Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas, Cell death & disease 13(2) (2022) 192.(IF:9.6,第一作者)
L. Gao, Q. Wang, W. Ren, J. Zheng, S. Li, Z. Dou, X. Kong, X. Liang, K. Zhi, The RBP1-CKAP4 axis activates oncogenic autophagy and promotes cancer progression in oral squamous cell carcinoma, Cell death & disease 11(6) (2020) 488.(IF:9.6,第一作者)
C.Y. Li, L. Gao, X.L. Fan, R.C. Zeng, D.C. Chen, K.Q. Zhi, In vitro degradation and cytocompatibility of a low temperature in-situ grown self-healing Mg-Al LDH coating on MAO-coated magnesium alloy AZ31, Bioactive materials 5(2) (2020) 364-376.(IF:20.3,第二作者)
L. Gao, Z.C. Dou, W.H. Ren, S.M. Li, X. Liang, K.Q. Zhi, CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK(½)/mTOR signaling pathways in oral squamous cell carcinomas, Cell death & disease 10(10) (2019) 745.(IF:9.6,第一作者)
Y. Zhi, W. Ren, S. Li, J. Zheng, J. Song, L. Gao, K. Zhi, Immune patterns of the tumor microenvironment in PD-L1(+) EGFR(+) HNSCC patients received anti-PD-1 and EGFR-based neoadjuvant therapy, Genes & diseases 13(4) (2026) 101902.(IF:9.4,共同通讯作者)
S. Li, W. Ren, J. Zheng, S. Li, K. Zhi, L. Gao, Role of O-linked N-acetylglucosamine protein modification in oxidative stress-induced autophagy: a novel target for bone remodeling, Cell communication and signaling : CCS 22(1) (2024) 358.(IF:8.9,通讯作者)
X. Yan, J. Zheng, W. Ren, S. Li, S. Yang, K. Zhi, L. Gao, O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology, Cell communication and signaling : CCS 22(1) (2024) 279.(IF:8.9,通讯作者)
S. Li, X. Yin, W. Ren, J. Zheng, S. Li, K. Zhi, L. Gao, Protein O-GlcNAcylation reprograms macrophage-mediated bone remodeling in medication-related osteonecrosis of the jaw, International journal of biological macromolecules 313 (2025) 144342.(IF:8.5,通讯作者)
Z. Zhu, S. Li, X. Yin, K. Sun, J. Song, W. Ren, L. Gao, K. Zhi, Review: Protein O-GlcNAcylation regulates DNA damage response: A novel target for cancer therapy, International journal of biological macromolecules 264(Pt 1) (2024) 130351.(IF:8.5,通讯作者)
K. Sun, Y. Zhi, W. Ren, S. Li, X. Zhou, L. Gao, K. Zhi, The mitochondrial regulation in ferroptosis signaling pathway and its potential strategies for cancer, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 169 (2023) 115892.(IF:7.5,共同通讯作者)
S. Li, L. Gao, J. Liu, C. Guo, J. Zheng, K. Zhi, W. Ren, The microRNA-10b-Bim axis promotes cancer progression through activating autophagy in oral squamous cell carcinoma, Cell death discovery 8(1) (2022) 373.(IF:7.0,共同第一作者)
L. Gao, B.Y. Peng, X.Q. Zhou, W.H. Ren, Modified parotidectomy for benign parotid tumors-case report, Asian journal of surgery (2024).(IF:3.8,第一作者)