口腔颌面外科学
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何冬梅

发布日期：2021-09-15　　 　　点击量：


博士，主任医师，教授，硕士研究生导师

工作经历：1996年本科毕业于北京医科大学口腔系；2001年获得北京大学口腔医学院口腔颌面外科专业博士学位，导师张益、张震康教授。之后在北京大学口腔医学院工作，历任主治医师和副主任医师。曾于2004年获得AO国际奖学金资助，在德国慕尼黑大学师从Michael Ehrenfield教授学习3个月。2005年获得国家留学基金委资助赴美国德克萨斯大学西南医学中心口腔颌面外科作访问学者1年，师从国际著名创伤专家Edward Ellis 3rd教授，之后在美国国际颅颌面、唇腭裂治疗中心作博士后研究2年，师从国际著名整形外科专家Kenneth Salyer和David Genecov教授。回国后于2008年7月作为引进人才到上海交通大学医学院附属第九人民医院工作。

科研方面：

包括颞下颌关节微创、重建及数字医学研究、骨关节炎的发病机制和骨-软骨再生等的研究。业务专长包括颞下颌关节外科、口腔颌面部正颌和创伤以及牙槽外科疾病的诊治。从业以来第一作者及通讯作者发表文章130余篇，其中SCI收录56篇。主持国家级和省部级课题13项（其中国自然2项），骨干参与2项科技部重点研发计划。参编专著10部，其中副主编专著1部,研究生规划教材1部，主译国外专著1部。授权专利14项，其中发明专利6项，1项转化北京爱康宜诚医疗器械有限公司70万元。

获奖及荣誉称号：

  1. 中华口腔医学会科技三等奖

  2. 华夏医学科技三等奖

  3. 上海卫生计生系统职工技术创新金奖

  4. 百丹特口腔医学教育二等奖

  5. 上海市第六期医务职工科技创新“星光计划”一等奖并获得“创新之星”称号

  6. 上海市职工合理化建议优秀成果

  7. 第32届上海市优秀发明选拔赛优秀发明银奖

  8. 上海市科技进步一等奖和教育部高校科技成果二等奖

学术任职：

  1. 中华口腔医学会颞下颌关节病学及牙合学专业委员会常委

  2. 第一届中华口腔医学会口腔颌面创伤及正颌专委会委员

  3. 上海口腔医学会口腔颌面外科专委会常务委员

  4. AO国际内固定协会亚太地区讲师

  5. 上海市医师协会口腔科医师分会第二届委员会秘书

  6. 中华口腔医学杂志、口腔颌面外科杂志、上海口腔医学杂志审稿人

  7. 国家科技奖励专家库专家

  8. 国家药监局器审中心专家

发表文章

  1. Zhu H, He D*, Yang Z, Lu C, Zhao J, Yang C. The effect of condylar reconstruction after different disc repositioning surgeries in adolescents with skeletal Class II malocclusion. 2021 Mar 22;S0278-2391(21)00304-9. doi: 10.1016/j.joms.2021.03.011. *通讯作者2020 IF: 1.642

  2. Zhong Y, Sun Q, He D*, Zou L, Lu C. Study on the lateral pterygoid muscle status after artificial temporomandibular joint replacement. Int J Oral Maxillofac Surg. 2021 Apr 3;S0901-5027(21)00103-X. doi: 10.1016/j.ijom.2021.03.008. Online ahead of print. *通讯作者 2020 IF: 2.068

  3. Zhu H, Yang Z*, He D*, Hu N, Cheng Z. The effect of TMJ disk repositioning by suturing through open incision on adolescent mandibular asymmetry with and without a functional orthodontic appliance. Oral Surg Oral Med Oral Pathol Oral Radiol. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Apr;131(4):405-414. doi: 10.1016/j.oooo.2020.11.014. Epub 2020 Dec 8. *通讯作者 2020 IF: 1.601

  4. Zou L, Zhong Y, Xiong Y, He D*, Li X, Lu C, Zhu H. A novel design of temporomandibular joint prosthesis for lateral pterygoid muscle attachment: A preliminary study. Front Bioeng Biotechnol. 2021 Jan 21;8:630983. doi: 10.3389/fbioe.2020.630983. eCollection 2020. *通讯作者 2020 IF: 3.644

  5. Zou L, He D*, Yang C, Lu C, Zhao J, Zhu H. Preliminary study of standard artificial temporomandibular joint replacement with preservation of muscle attachment. J Oral Maxillofac Surg. 2020 Dec 17:S0278-2391(20)31509-3. doi: 10.1016/j.joms.2020.12.012. Online ahead of print. *通讯作者 2020 IF: 1.642

  6. Xi Yu, Yihui Hu, Luxiang Zou, Shifeng Yan, Huimin Zhu, Kunxi Zhang*, Wenguang Liu*, Dongmei He*, Jingbo Yin*. A Bilayered Scaffold with Segregated Hydrophilicity-Hydrophobicity Enables Reconstruction of Goat Hierarchical Temporomandibular Joint Condyle Cartilage. Acta Biomater. 2021 Feb;121:288-302. doi: 10.1016/j.actbio.2020.11.031. Epub 2020 Nov 22. *通讯作者 2020 IF, 7.242

  7. Lu C, Xie Q, He D*, Yang C. Stability of Orthognathic Surgery in the Treatment of Condylar Osteochondroma Combined with Jaw Deformity by CT Measurements. J Oral Maxillofac Surg. 2020 Aug;78(8):1417.e1-1417.e14. doi: 10.1016/j.joms.2020.03.025. Epub 2020 Apr 2. *通讯作者 2020 IF, 1.642

  8. Zhu H, Hu Y, Wang C, Zhang X, He D*. CircGCN1L1 promotes synoviocyte proliferation and chondrocyte apoptosis by targeting miR-330-3p and TNF-α in TMJ osteoarthritis. Cell Death Dis. 2020;11(4):284. Published 2020 Apr 24. doi:10.1038/s41419-020-2447-7. *通讯作者 2020 IF, 6.304

  9. Hu Y, Zhu H, Bu L, He D*. Expression profile of circular RNAs in TMJ osteoarthritis synovial tissues and potential functions of has_circ_0000448 with specific back-spliced junction. Am J Transl Res. 2019 Sep 15;11(9):5357-5374. eCollection 2019. *通讯作者。2019年IF: 3.375.

  10. Zou L, Zhao J*, He D*. Preliminary clinical study of Chinese standard alloplastic temporomandibular joint prosthesis. J Craniomaxillofac Surg. 2019 Apr;47(4):602-606. doi: 10.1016/j.jcms.2019.01.045. Epub 2019 Feb 4. 2019年IF: 1.766

  11. Zhu H, He D*, Yang Z*, Song X, Ellis E 3rd. The effect of disc repositioning and post-operative functional splint for the treatment of anterior disc displacement in juvenile patients with class II malocclusion. J Craniomaxillofac Surg. 2019 Jan;47(1):66-72. doi: 10.1016/j.jcms.2018.09.035. Epub 2018 Nov 14. 2019年IF: 1.766

  12. Zhou Q, Zhu H, He D*, Yang C, Song X, Ellis E. Modified temporomandibular joint disc repositioning with miniscrew anchor: Part II—Stability evaluation by Magnetic Resonance Imaging. J Oral Maxillofac Surg. 2019 Feb;77(2):273-279. doi: 10.1016/j.joms.2018.07.016. Epub 2018 Jul 24. 2019年IF:1.642

  13. Zhao J, Zou L, He D*, Ellis E 3rd. Comparison of bone adaptation after modification in Biomet standard alloplastic temporomandibular joint prostheses. J Craniomaxillofac Surg. 2018 Oct;46(10):1707-1711. doi: 10.1016/j.jcms.2018.07.024. Epub 2018 Aug 3. IF: 1.942

  14. Wang F, Hu Y, He D*, Zhou G*, Ellis E 3rd. Scaffold-free cartilage cell sheet combined with bone-phase BMSCs-scaffold regenerate osteochondral construct in mini-pig model. Am J Transl Res. 2018 Oct 15;10(10):2997-3010. eCollection 2018. IF: 3.266

  15. Zou L, Zhang L, He D*, Yang C, Zhao J, Ellis E. Clinical and radiologic follow-up of Zimmer Biomet stock total temporomandibular joint replacement after surgical modifications. J Oral Maxillofac Surg. 2018 Dec; 76(12):2518-2524. doi: 10.1016/j.joms.2018.06.013. Epub 2018 Jun 14. IF:1.781

  16. He D*, Yang C, Zhu H, Ellis E. Temporomandibular joint disc repositioning by suturing through open incision: A technical note. J Oral Maxillofac Surg. 2018 May;76(5):948-954. doi: 10.1016/j.joms.2017.12.006. Epub 2017 Dec 13. IF:1.781

  17. Zou L, He D*, Ellis E. A Comparison of Clinical Follow-Up of Different Total Temporomandibular Joint Replacement Prostheses: A Systematic Review and Meta-Analysis. J Oral Maxillofac Surg. 2018 Feb;76(2):294-303. doi: 10.1016/j.joms.2017.08.022. Epub 2017 Aug 24. Review. *通讯作者IF:1.781

  18. Yang X, Lu C, Dong M, He D*, Yang C*, Hu Y. Evaluation of the condyle remodeling after lateral arthroplasty in growing children with temporomandibular joint ankylosis. Sci Rep. 2017 Aug 30;7(1):9922. doi: 10.1038/s41598-017-09425-5. *通讯作者IF: 4.122

  19. Zhao J, He D*, Yang C, Lu C, Hu Y, Huang D, Ellis E 3rd. 3-D computed tomography measurement of mandibular growth after costochondral grafting in growing children with temporomandibular joint ankylosis and jaw deformity. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Oct; 124(4): 333-338. doi: 10.1016/j.oooo.2017.06.002. Epub 2017 Jun 13. IF: 1.718

  20. Wang F, Hu Y, He D*, Zhou G*, Yang X, Ellis E. Regeneration of subcutaneous tissue-engineered mandibular condyle in nude mice. J Craniomaxillofac Surg. 2017 Jun; 45(6): 855-861. doi: 10.1016/j.jcms.2017.03.017. Epub 2017 Apr 4. 共同第一作者。*共同通讯作者, IF: 1.96

  21. Hu Y, Zhang L, He D*, Yang C*, Chen M, Zhang S, Li H, Ellis E III. Simultaneous treatment of temporomandibular joint ankylosis with severe mandibular deficiency by standard TMJ prosthesis. Sci Rep. 2017 Mar 24;7:45271. doi: 10.1038/srep45271. 共同第一作者，*通讯作者, IF: 4.122

  22. Lu C, He D*, Yang C, Huang D, Ellis E. Computer-assisted surgical planning and simulation for unilateral condylar benign lesions causing facial asymmetry. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Apr;123(4):453-458. doi: 10.1016/j.oooo.2016.11.013. *通讯作者，IF: 1.718

  23. Wang F, Sun Y, He D*, Wang L. Effect of Concentrated Growth Factors on the Repair of the Goat Temporomandibular Joint. J Oral Maxillofac Surg. 2017 Mar;75(3):498-507. doi: 10.1016/j.joms.2016.09.006. 王飞宇，孙玉环共同第一作者。*通讯作者，2017年IF: 1.779

  24. He D*, Yang X, Wang F, Yang C*, Dong M. Acute trauma induced disc displacement without reduction and its sequelae. Sci Rep. 2016 Sep 1;6:32684. doi: 10.1038/srep32684. IF, 4.259。杨秀娟、王飞宇共同第一作者。*通讯作者。

  25. Wang BL, He DM*, Yang C*, Cai YH, Cai XY, Yang XJ, Ma ZG. Factors affecting the outcomes of non-surgical treatment for intracapsular condylar fractures. Int J Clin Exp Med. 2016; 9(6): 10847-10855. *通讯作者IF: 1.069

  26. Zhou Q, Sun Y, Zhang P, He D*, Abdelrehem A, Shi H, Zhang L, Zheng J. Simultaneously blocking necrosis and apoptosis to protect TMJ chondrocytes from TNF-alpha induced death: a preliminary study. Int J Clin Exp Med. 2016; 9(2): 2202-2210. *通讯作者IF: 1.069

  27. Zhang LZ, Meng SS, He DM*, Fu YZ, Liu T, Wang FY, Dong MJ, Chang YS.  Three-Dimensional Measurement and Cluster Analysis for Determining the Size Ranges of Chinese Temporomandibular Joint Replacement Prosthesis. Medicine 2016, 95(8): e2897. IF: 1.803 *通讯作者

  28. Huang D, Lu C, Yao Z, He D*, Yang C*. A comparison of the effect between coronoid process graft and costochondral graft in the reconstruction of temporomandibular joint. J Craniofac Surg. 2016 Mar;27(2):e197-200. IF: 0.788 *通讯作者

  29. Bai G, Yang C*, He D*, Zhang X, Abdelrehem A. Application of fossa bone graft to stabilize stock total joint prosthesis in temporomandibular joint surgery. J Cranio-maxillofac Surg. 2015; 43(8): 1392-1397. IF: 1.592 *通讯作者

  30. Yang X, Yao Z, He D*, Cai Y, Dong M, Yang C. Does Soft Tissue Injury Affect Intracapsular Condylar Fracture Healing? J Oral Maxillofac Surg. 2015; 73(11): 2169-2180. IF: 1.631 *通讯作者

  31. Huang D, Chen M, He D*, Yang C*, Yuan J, Bai G, Wang Y, Wei W, Chen Z. Preservation of the inferior alveolar neurovascular bundle in the osteotomy of benign lesions of the mandible using a digital template. Br J Oral Maxillofac Surg. 2015; 53(7): 637-641. IF: 1.237 *通讯作者

  32. Li L, Wang L, Sun Yuhuan, Yang C, He D*. Establishment and histological evaluation of a goat traumatic temporomandibular joint model. J Oral Maxillofac Surg. 2015 May; 73(5): 943-950. IF: 1.631 *通讯作者

  33. Xie Q, Yang C*, He D*, Cai X Ma Z. Is mandibular asymmetry more frequent and severe with unilateral disc dispacement? J Cranio-maxillofac Surg 2015 Jan;43(1):81-6. IF: 1.592 *通讯作者

  34. Lu C, He D*, Yang C, Wilson JJ. The use of computer-assisted templates for placement of osteotomies in lateral gap arthroplasty. J Oral Maxillofac Surg. 2015 Jan; 73(1): 30-38. IF：1.631*通讯作者

  35. He D, Yang C*, Zhang S, Wilson JJ. Modified Temporomandibular Joint Disc Repositioning with Mini Screw Anchor: part I – surgical technique. J Oral Maxillofac Surg. 2015 Jan; 73(1): 47e1-e9. IF：1.631

  36. Bai Guo, He D*, Yang C, Chen M, Yuan J, Wilson JJ. Application of Digital Templates to Guide Total Alloplastic Joint Replacement Surgery with Biomet Standard Replacement System. J Oral Maxillofac Surg. 2014 Dec; 72(12): 2440-2452.IF：1.425 *通讯作者

  37. Lu C, Huang D, He D*, Yang C, Yuan J. Digital Occlusal Splint for Condylar Reconstruction in Children With Temporomandibular Joint Ankylosis. J Oral Maxillofac Surg. 2014 Aug;72(8):1585-93. IF：1.425 *通讯作者

  38. Bai G, He D*, Yang C*, Lu C, Huang D, Chen M, Yuan J. Effect of Digital Template in the Assistant of a Giant Condylar Osteochondroma Resection. J Craniofac Surg. 2014 May;25(3):e301-4.IF：0.678 *通讯作者

  39. He D, Cai Y, Yang C*. Analysis of temporomandibular joint ankylosis caused by condylar fracture in adults. J Oral Maxillofac Surg. 2014 Apr;72(4):763.e1-9. IF：1.425 *通讯作者

  40. Lu C, He D*, Yang C. Which craniofacial fractures are associated with external auditory canal bleeding? J Oral Maxillofac Surg. 2014 Jan;72(1):121-6.IF：1.425 *通讯作者

  41. Li L, Feng Z, Ma R, Yang C*, He D*. The comparative study of mandibular ramus growth with different treatment methods for intracapsular condylar fracture. J Craniofac Surg. 2013 Mar;24(2):657-670. *通讯作者 IF:0.686

  42. Huang D, He D*, Yang C*, Chen MJ, Zhou Q, Dong MJ. Computer-assisted local resection  for exostosis osteochondroma of the mandibular condyle. J Craniofac Surg. 2013 Jul;24(4):e446-9. *通讯作者 IF:0.686

  43. He D, Yang C*, Chen M, Yang X, Li L. Effects of soft tissue injury to the temporomandibular joint: report of 8 cases. Br J Oral Maxillofac Surg. 2013 Jan;51(1):58-62. IF: 1.133 *通讯作者

  44. He D, Huang D, Yang C, Gou H. Application of computer-assisted design and manufacture technique in the treatment of condylar osteochondroma combined with jaw bone deformities: Report of a case. J Oral Maxillofac Surg, Medicine, and Pathology. 2013; 25(1): 46-51.

  45. He D, Yang C*, Shen G, Chen M, Yang X, Huang D, Zhou Q, Guo Z, Wang P, Ye M. Navigation-guided resection for a tenosynovial giant cell tumor involving the temporomandibular joint and skull base. J Craniofac Surg. 2012 Mar; 23(2): 521-523. IF:0.686 *通讯作者

  46. He D, Li Z, Shi W, Sun Y, Zhu H, Lin M, Shen G, Fan X*. Orbitozygomatic Fractures with Enophthalmos: Analysis of 64 Cases Treated Late. J Oral Maxillofac Surg. 2012 Mar; 70(3): 562-576. IF: 1.333 *通讯作者

  47. Feng Z, Li L, He D*, Yang C*, Qiu Y. Role of retention of the condylar cartilage in open treatment of intracapsular condylar fractures in growing goats: three-dimensional computed tomographic analysis. Br J Oral Maxillofac Surg. 2012 Sep;50(6):523-527. *通讯作者。IF: 2.717

  48. Wang Y, He D*, Yang C, Wang B, Qian W. An easy way to apply orthodontic extraction for impacted lower third molar compressing to the inferior alveolar nerve. J Craniomaxillofac Surg. 2012 Apr; 40(3): 234-237. *通讯作者。IF: 1.61

  49. He D, Yang C*, Chen M, Yang X, Li L, Jiang Q. Surgical treatment of traumatic temporomandibular joint ankylosis with medially displaced residual condyle: surgical methods and long-term results. J Oral Maxillofac Surg. 2011;69(9):2412-2418. IF:1.64 *通讯作者

  50. He D, Yang C*, Chen M, Zhang X, Qiu Y, Yang X, Li L, Fang B. Traumatic Temporomandibular Joint Ankylosis: Our Classification and Treatment Experience. J Oral Maxillofac Surg. 2011;69(6):1600-1607. IF:1.64 *通讯作者

  51. He D, Genecov DG*, Barcelo R. Nonunion of the external maxillary distraction in cleft lip and palate: analysis of possible reasons. J Oral Maxillofac Surg 2010;68(10):2402-2411. IF:1.50 *通讯作者

  52. He D, Yang C*, Chen M, Bin J, Zhang X, Qiu Y. Modified preauricular approach and rigid internal fixation for intracapsular condyle fracture of the mandible. J Oral Maxillofac Surg 2010;68(7):1578-1584. IF:1.50 *通讯作者

  53. He D, Genecov DG*, Herbert M, Barcelo R, Elsalanty ME, Weprin BE, Opperman LA*. Effect of recombinant human bone morphogenetic protein-2 on bone regeneration in large defects of the growing canine skull after dura mater replacement with a dura mater substitute. J Neurosurg. 2010 Feb;112(2):319-328. IF:2.739. *通讯作者

  54. He D, Yang C*, Chen M, Jiang B, Wang B. Intracapsular Condylar Fracture of the Mandible: our classification and open treatment experience. J Oral Maxillofac Surg.2009;67(8):1672-1679. IF:1.58 *通讯作者

  55. He D, Ellis E 3rd*, Zhang Y. Etiology of temporomandibular joint ankylosis secondary to condylar fractures: the role of concomitant mandibular fractures. J Oral Maxillofac Surg. 2008; 66: 77-84. IF: 1.241 *通讯作者

  56. He D, Zhang Y*, Ellis E 3rd. Panfacial fractures: Analysis of 33 cases treated late. J Oral Maxillofac Surg. 2007; 65: 2459-2465. IF: 1.37 *通讯作者

  57. He D, Blomquist PH, Ellis E 3rd*. Association between ocular injuries and internal orbital fractures. J Oral Maxillofac Surg. 2007; 65: 713-720. IF: 1.37 *通讯作者



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